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US grant · National Institutes of Health

HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)

Up to $350,000 Closes January 15, 2027

Official listing and how to apply Full funding notice

Source: Grants.gov · Last checked

Key facts

FunderNational Institutes of Health
Part ofDepartment of Health and Human Services
Opportunity numberRFA-NS-25-023
Amount per awardUp to $350,000
OpensSeptember 18, 2024
ClosesJanuary 15, 2027 (66 days left)
Who can applySchools and universities, Businesses, Government, Nonprofits, Other (see listing), Tribal organizations
Applicant types listedState governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; Independent school districts; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Small businesses; Special district governments; Private institutions of higher education; Public and State controlled institutions of higher education; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities
State or areaNationwide
Cost sharing or matchNot required
StatusOpen
SourceGrants.gov
Last checkedNovember 10, 2026

About this grant

Summary from the official listing on Grants.gov:

This funding opportunity is part of a suite of NOFOs within the NIH HEAL Initiative to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal is to encourage initial translational efforts that will support a drug discovery program and advance projects to the point where they meet the entry criteria for the Pain Therapeutics Development Program. The scope will therefore be focused on development of assays to support a distinct testing funnel, screening efforts to identify hits, and initial characterization of hits and potential therapeutic agents (including small molecules, biologics, and natural products).

Eligibility

Other Eligible Applicants include the following:

Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

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