US grant · Michael S Zarkin Grants Management Specialist
The Genesis Mission: Transforming Science and Energy with AI
$500,000 to $16,000,000 Closes December 17, 2026
Official listing and how to apply
Source: Grants.gov · Last checked
Key facts
| Funder | Michael S Zarkin Grants Management Specialist |
|---|---|
| Part of | Department of Energy - Office of Science |
| Opportunity number | DE-FOA-0003612 |
| Amount per award | $500,000 to $16,000,000 |
| Total funding available | $293,760,000 |
| Opens | March 17, 2026 |
| Closes | December 17, 2026 (37 days left) |
| Who can apply | Open to anyone |
| Applicant types listed | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility" |
| State or area | Nationwide |
| Cost sharing or match | Required |
| Status | Open |
| Source | Grants.gov |
| Last checked | November 10, 2026 |
About this grant
Summary from the official listing on Grants.gov:
The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Teams are encouraged to leverage the extensive scientific and data resources of the DOE/National Nuclear Security Administration (NNSA), the National Laboratories, U.S. industry, and academia. The resulting AI models and workflows, if successful, may be integrated into the American Science Cloud.
DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas: advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy (see specific focus areas in Section III Program Descriptions).
In addition, this RFA will remain available to allow the recipients of FY26 Phase I awards to apply for larger team Phase II awards. In a few weeks, DOE plans to amend the RFA to clarify the LOI and application guidelines for FY26 Phase II awards. In FY27, DOE plans to amend the RFA or to issue an alternative funding opportunity to update the topic and focus areas to allow a second competition of Phase I small team applications and Phase II large team applications.
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